TRANSLATIONAL PHYSIOLOGY Role of receptor-mediated endocytosis in the antiangiogenic effects of human T lymphoblastic cell-derived microparticles
نویسندگان
چکیده
Chun Yang,* Wei Xiong,* Qian Qiu, Zuo Shao, David Hamel, Houda Tahiri, Grégoire Leclair, Pierre Lachapelle, Sylvain Chemtob, and Pierre Hardy Departments of Pediatrics and Pharmacology, Research Center of Centre hospitalier universitaire Sainte-Justine, University of Montreal, Montreal, Quebec, Canada; Department of Pulmonology, Chongqing Southwest Hospital, Chongqing, China; Faculty of Pharmacy University of Montreal, Montreal, Quebec, Canada; and Departments of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada
منابع مشابه
Role of receptor-mediated endocytosis in the antiangiogenic effects of human T lymphoblastic cell-derived microparticles.
Microparticles possess therapeutic potential regarding angiogenesis. We have demonstrated the contribution of apoptotic human CEM T lymphocyte-derived microparticles (LMPs) as inhibitors of angiogenic responses in animal models of inflammation and tumor growth. In the present study, we characterized the antivascular endothelial growth factor (VEGF) effects of LMPs on pathological angiogenesis i...
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